Manjishta for Beauty and Brains.
Manjishta is a well-known blood purifier and is used for a clear skin. This property is because it improves microcirculation in the skin. Of late, it is found that the microcirculation plays a great role in our physical well-being. It is the largest and functionally most important component of circulation in the human organism. It is active in the fine, extensive network of the smallest blood vessels which is more complex than that of the vast network of roots of a tree. Although the human network is considerably more detailed than that of a tree, for example, it is nonetheless a good example for illustrating how important the small vessels are for “on site” supply.
Microcirculation, essentially, is the system by which the oxygenated blood is made available to each and every tissue and organ of the body. Arteries branch down to small arterioles (10-100 µm in diameter) which in turn branch to capillaries (5-8 µm in diameter) where substance and gas exchange between blood and interstitial fluid takes place . Blood then oozes out to interstitial fluid, cells and tissues. The deoxygenated blood is then collected by venules which in turn pass the impure blood to veins (10-200 µm in diameter). In addition to these blood vessels, the microcirculation also includes lymphatic capillaries and collecting ducts. The main functions of the microcirculation are the delivery of oxygen and nutrients and the removal of CO2. It also serves to regulate blood flow and tissue perfusion thereby affecting blood pressure and responses to inflammation which can include edema (swelling).
Approximately, seven percent of the body’s blood is in the capillaries which continuously exchange substances with the liquid outside these blood vessels, called interstitial fluid. This dynamic displacement of materials between the interstitial fluid and the blood is named capillary exchange. Due to the large number (10-14 million ) of capillaries, there is an incredible amount of surface area for exchange. The substances pass through capillaries through three different systems or mechanisms: diffusion, bulk flow, and transcytosis or vesicular transport. The liquid and solid exchanges that take place in the microvasculature particularly involve capillaries and post-capillary venules and collecting venules.
The main functions of the microcirculation include the regulation of:
1. blood flow and tissue perfusion,
2. blood pressure,
3. tissue fluid (swelling or edema),
4. delivery of oxygen and other nutrients and removal of CO2 and other metabolic waste products, and
5. body temperature.
In addition, microcirculation interacts extensively with the immune system and the body’s defense mechanisms. A restricted or defective microcirculation results in a faster aging of cells and is the cause of a number of health complaints and illnesses. The pivotal role of microcirculation in many disease conditions is well established. Indeed, microcirculation abnormalities often occur in subjects with high blood pressure. Also, metabolic diseases such as dislipidemia and type-2 diabetes induce destructive changes in the microvascular system that feeds the heart, the retina and the kidneys. As a consequence, early symptoms affecting patients, often the first signs of an underlying and more serious disease, can be due to a disturbance of microcirculation. Thus, microcirculation is an essential factor, albeit often poorly recognized, in the pathogenesis of many disease conditions.